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For any possible questions, please, contact me! NEW 100 % ORIGINAL TRACKING NUMBER THANK YOU FOR VISITING MY LOT It is very important !!! Item will be shipped from Russia for 2-3 days and free shipping takes 14 to 21 days
NEW 100 % ORIGINAL
THANK YOU FOR VISITING MY LOT
Spasmolytic agent Dosage form Transparent liquid from light yellow to intensely yellow color or from greenish-yellow to intensely yellow with a greenish tinge. Composition 1 amp.
Drotaverina hydrochloride 40 mg
Auxiliary components: sodium disulfite, ethanol, water for injections pharmachologic effect Myotropic antispasmodic. Reduces the intake of calcium ions in the smooth muscle cells (inhibits phosphodiesterase, leads to the accumulation of intracellular cAMP). Reduces the tone of the smooth muscles of internal organs and intestinal motility, dilates the blood vessels. Does not affect the autonomic nervous system, does not penetrate the central nervous system. The presence of a direct effect on smooth muscles can be used as an antispasmodic in cases where drugs from the group of M-holinoblokatorov (closed-angle glaucoma, prostatic hyperplasia) are contraindicated.
With parenteral administration, the drug appears in 2-4 minutes. The maximum effect occurs after 30 minutes. Pharmacokinetics Evenly distributed on the tissues, penetrates into the smooth muscle cells. Communication with blood plasma proteins — 95-98%. The half-life is 2-4 hours. It is mainly excreted by the kidneys, to a lesser extent with bile. Does not penetrate the blood-brain barrier. Dosage Intramuscularly or subcutaneously, 2-4 ml (40-80 mg) 1-3 times a day. Duration of treatment is 1-2 weeks. If necessary, prolonged treatment is transferred to taking the drug inside. In cases where a rapid effect is needed, 2-4 ml (40-80 mg) of the drug is injected slowly into 10-20 ml of a 0.9% solution of sodium chloride or a 5% solution of dextrose. Children under 6 years are usually administered at a dose of 10-20 mg 1-2 times a day, children older than 6 years — in a dose of 20 mg 1-2 times a day.