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Usa/canada delivered time 15-20 business days.
Australia/Asia delivered time 15-26 business days.
For any possible questions, please, contact me! NEW 100 % ORIGINAL TRACKING NUMBER THANK YOU FOR VISITING MY LOT It is very important !!! Item will be shipped from Russia for 2-3 days and free shipping takes 14 to 21 days
NEW 100 % ORIGINAL
THANK YOU FOR VISITING MY LOT
Drug Form Spray for topical use dosed with 10% as a colorless alcohol solution with a characteristic menthol odor. Composition 1 fl. Lidocaine 3.8 g ± 10% Excipients: peppermint oil, propylene glycol, ethanol 96%. Pharmacological action Local anesthetic, acetanilide derivative. It has the properties of an antiarrhythmic agent of class I B and membrane stabilizing activity. Provides local anesthesia by blocking generation and conducting pulses in nerve endings. The mechanism of action is associated with the stabilization of the permeability of the membrane of neurons for sodium ions. The threshold of electrical excitability rises. Reaching the larynx and trachea, the drug suppresses the pharyngeal reflex and oppresses the cough reflex, which can lead to aspiration, bronchopneumonia. At therapeutic doses, it usually does not affect the strength and heart rate. The action of lidocaine in the form of an aerosol develops within 1 minute and lasts 5-6 minutes. The achieved sensitivity decrease slowly disappears within 15 minutes. Pharmacokinetics Absorption In topical application on mucous membranes, lidocaine is absorbed to varying degrees, depending on the dose and site of application. The speed of perfusion in the mucosa affects suction. Lidocaine is well absorbed from the respiratory tract, which requires caution and prevents the possibility of administration in toxic doses.
Dosage Aerosol is sprayed onto the mucous membranes. At each spraying of 1 portion of the aerosol, 4.8 mg of lidocaine is released to the surface. The dose depends on the indications and the area of the anesthetized surface. To avoid a high concentration of lidocaine in the blood plasma should be used the lowest dose, providing a satisfactory effect. Usually, 1-3 sprays are sufficient, although 15-20 sprays are used in obstetrics (maximum dose is 40 sprays / 70 kg of body weight). Approximate doses (number of sprays) for different indications: Area of application Dose (number of sprays) Dentistry 1-3 Oral surgery 1-4 Otorhinolaryngology 1-4 Endoscopy 2-3 Obstetrics 15-20 Gynecology 4-5 Dermatology 1-3 With impregnated The tampon preparation can be applied to large surfaces. In children under 2 years of age, the drug is preferably applied by tampon, which avoids the fear of spraying and the burning sensation. For patients with hepatic and / or heart failure, a dose reduction of 40% is recommended. When using aerosol, the balloon should be kept in an upright position.