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NOOPEPT. Brain Booster. 200 tablets.(4boxX50) 10 mg.
ethyl N-phenylacetyl-L-prolylglycine (noopept®) 10 mg
Other ingredients: microcrystalline cellulose, lactose (milk sugar), potato starch, povidone, magnesium stearate.
Neuroprotective drugs. Has nootropic and neuroprotective effects. Improves learning ability, memory, operating at all phases of the process: the initial processing of information consolidation, extraction. Prevents the development of amnesia caused by electric shock, blockade of central cholinergic structures glutamatergic receptor systems, deprivation of paradoxical sleep phase.
The neuroprotective effect of the drug is to increase the stability of brain tissue to damaging influences (trauma, hypoxia, or electroconvulsive toxic effect) and weakening of the extent of damage to neurons in the brain. The drug chamber to reduce the volume of thrombotic stroke models and prevents neuronal death in the tissue culture of cerebral cortex and cerebellum, exposed to neurotoxic glutamate concentrations, free-radical oxygen.
Noopept® has an antioxidant effect. Marked antagonistic effect on the effects of excess calcium. Improves blood rheology, having antiplatelet, fibrinolytic, anticoagulant properties.
Nootropic action of the drug associated with the formation tsikloprolilglitsina similar structure endogenous cyclic dipeptide possessing antiamnestic activity and the presence holinopozitivnogo action.
Noopept® increases the amplitude of transcallosal response, facilitating associative connections between the hemispheres of the brain at the level of cortical structures.
Noopept® the recovery of memory and other cognitive functions, disturbed as a result of the damaging effects — brain trauma, local and global ischemia, prenatal damage (alcohol, hypoxia).
The therapeutic effect of the drug in patients with organic diseases of the CNS manifested with 5-7 days of treatment. Initially implemented anxiolytic and easy-stimulating effects, manifested in the reduction or disappearance of anxiety, irritability, affective lability, sleep disorders. After 14-20 days of treatment revealed a positive effect of the drug on cognitive function, attention and memory parameters.
Noopept® has vegetonormalizuyuschim action, reduces headaches, postural disorders, tachycardia.
Noopept® not accumulates in the body, does not cause drug dependence. To remove the drug is not observed withdrawal.
Noopept® has no damaging effect on the internal organs, does not change the hematological and biochemical parameters, has no immunotoxic, teratogenic, mutagenic properties does not show.
Absorbed from the gastrointestinal tract. In unaltered absorbed into the systemic circulation. Cmax is achieved at a mean of 15 minutes. Bioavailability — 99.7%.
Penetrate the BBB. In the brain is determined in large concentrations than in the blood.
Metabolism and excretion
The drug is partially retained in unmodified form, partially metabolized with the formation of phenylacetic acid and fenilatsetilprolina tsikloprolilglitsina.
T1 / 2 — 0.38 hours.
Possible: allergic reactions. In patients with hypertension, mostly severe, while taking the drug may be a rise in blood pressure.
Patients should be informed that the need to increase the dose (30 mg /), long-term use, as well as the simultaneous use of other drugs, the emergence of side effects or worsening of your condition, consult your doctor.
Impaired memory, attention and other cognitive functions and emotionally labile disorder (including elderly patients) at:
— Effects of traumatic brain injury;
— Commotion syndrome;
— Cerebrovascular insufficiency (encephalopathy different genesis);
— Asthenic disorders;
— Other states with evidence of an impairment of intellectual productivity.
— Expressed human liver;
— Pronounced renal dysfunction;
— Lactation (breastfeeding);
— Childhood and adolescence to 18 years;
— Hypersensitivity to the drug.
Not found Noopept interaction with alcohol, drugs, antihypertensive drugs and drugs stimulating effect.
Noopept® used inside, after a meal. The drug is administered in an initial dose of 20 mg — 10 mg in 2 divided doses (morning and afternoon). With the lack of treatment efficacy and good tolerability of the drug dose was increased to 30 mg — 10 mg in 3 divided doses throughout the day. You should not take the drug within 18 hours. The duration of the course of treatment is 1.5-3 months. A second course of treatment, if necessary, can be carried out after 1 month.
Specific symptoms of overdose is not installed