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NEW 100 % ORIGINAL
THANK YOU FOR VISITING MY LOT
The composition of the calcium hopantenate (Pantogam) 500 mg, excipients — methylcellulose 1.6 mg, calcium stearate 6.2 mg, magnesium hydroxycarbonate 93,6 mg, talc and 18.6 mg. Pharmacological action the Spectrum of action of Pantogam is associated with the presence in its structure gamma-aminobutyric acid. The mechanism of action is due to a direct effect of Pantogam GIMCV-receptor-channel complex. The drug has nootropic and anticonvulsant effect. Pantogam increases a brain resistance to hypoxia and exposure to toxic substances, stimulates anabolic processes in neurons, combines a moderate sedative action with a soft stimulating effect, reduces the excitability of the motor, activates mental and physical performance. Improves GABA metabolism in chronic alcohol intoxication and after ethanol withdrawal. It is able to inhibit the acetylation reactions involved in the mechanisms of procaine (novocaine) and sulfonamides inactivation, thereby achieving the prolongation of the latter. Causes inhibition of pathologically increased bubble reflex and tone detrusor. Pharmacokinetics Pantogam is rapidly absorbed from the gastrointestinal tract, penetrates the blood-brain barrier, the highest concentrations are in the liver, kidneys, stomach and skin. The drug is not metabolized and excreted unchanged for 48 hours: 67.5% of the dose – with urine, 28.5% – with feces.
Indications of cognitive disorders in organic brain lesions (including the consequences neuroinfections and traumatic brain injury) and neurotic disorders, schizophrenia with organic cerebral insufficiency; cerebrovascular insufficiency caused by atherosclerotic changes of cerebral vessels; extrapyramidal disorders (myoclonus-epilepsy, Huntington’s chorea, hepatolenticular degeneration, Parkinson’s disease, etc.), and also for the treatment and prevention of extrapyramidal syndrome (hyperkinetic and akinetic) caused by neuroleptics; epilepsy with a slowdown in mental processes in complex therapy with anticonvulsants; psycho-emotional overload, reduced mental and physical performance, to improve concentration and memory; neurogenic urination disorders (pollakiuria, imperative urge, imperative urinary incontinence, enuresis); children with perinatal encephalopathy, mental retardation Contraindications Hypersensitivity, acute severe kidney disease, pregnancy, lactation.
Dosage Inside through 15-30 minutes after eating, Single dose for adults is usually 0.25-1 g, for children – 0.25-0.5 g; daily dose for adults is 1.5-3 g, for children – 0,75-3 g. the Course of treatment – from 1 to 4 months, in some cases up to 6 months. After 3-6 months, it is possible to conduct a repeated course of treatment. With epilepsy in combination with anticonvulsants at a dose of 0.75 to 1 g per day. The course of treatment up to 1 year and more. When extrapyramidal neuroleptic syndrome in combination with ongoing therapy, the daily dose to 3 g, treatment within several months. In extrapyramidal hyperkinesis in patients with hereditary diseases of the nervous system in combination with the therapy from 0.5 to 3 g per day. The course of treatment up to 4 months or more. At consequences of neuroinfections and traumatic brain injuries to 0.25 g 3-4 times a day. To restore performance at high loads and asthenic conditions Pantogam appoint 0.25 g 3 times a day. For the treatment of extrapyramidal syndrome caused by neuroleptics: adults 0.5 — 1 g 3 times a day, children – 0.25-0.5 g 3-4 times a day. The course of treatment is 1-3 months. When ticks: children 0.25-0.5 g 3-6 times a day for 1-4 months. When urinary disorders: adults-0,5-1 g 2-3 times a day, children-0.25-0.5 g (daily dose is 25-50 mg/kg). The course of treatment from 1 to 3 months. Children with various pathology of nervous system depending on age the preparation is recommended in a dose of 1-3 g. the Tactics of the purpose of the drug: escalating doses for 7-12 days, receiving a maximum dose for 15-40 days and gradually decrease the dose until the abolition of Pantogam for 7-8 days. The break between the course receptions Pantogama, as for any other nootropic agent, is from 1 to 3 months. In long-term treatment is not recommended simultaneous administration of the drug with other nootropic and stimulants. Taking into account the nootropic effect of the drug, its administration is preferably carried out in the morning and afternoon.